Pyewacket may refer to:
- Pyewacket (familiar spirit), a familiar spirit, reported by an alleged witch in 1644
- Pyewacket, Gillian Holroyd's cat and familiar in the film <i>Bell, Book and Candle
- Pyewacket (novel), a 1967 children's novel by Rosemary Weir
- Pywacket, a hybrid orchid of the genus Cymbidium
- Pyewacket (yacht), a MaxZ86-class sailing yacht commissioned in 2004 by Roy E. Disney; also a Santa Cruz 70 sailed by the Disney family.
- Pye Wacket, an experimental missile
- Pyewackett, Electric folk band remembered for updating 18th century songs with modern harmonies and inventive instrumentation.
- Pyewacket (film), 2017 Canadian film directed by Adam MacDonald.
