Museum of Science and Industry may refer to:
United Kingdom
CALIFORNIA SCIENCE CENTER - FREE TOUR AT CALIFORNIA SCIENCE CENTER IN LOS ANGELES.
- Museum of Science and Industry, Birmingham in Birmingham, England, closed in 1997
- Museum of Science and Industry (Manchester) (MOSI), Manchester, England
- National Museum of Science and Industry (NMSI), a collection of British museums
United States
- Museum of Science and Industry (Chicago) (MSI), Chicago, Illinois
- Museum of Science & Industry (Tampa) (MOSI), Tampa, Florida
- California Museum of Science and Industry, Los Angeles, California, a former museum replaced by the California Science Center
- Oregon Museum of Science and Industry (OMSI), Portland, Oregon